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Keywords: namespace briefcase
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion\explorer\Desktop\NameSpace\
Look under the virtual folder names, and you should see the data item named "Briefcase". Then use RegDelValue to delete it.
For reference, here are the virtual folders:
Dial-Up Networking. {992CFFA0-F557-101A-88EC-00DD010CCC48} Printers. {2227A280-3AEA-1069-A2DE-08002B30309D} Inbox. {00020D75-0000-0000-C000-000000000046} My Computer. {20D04FE0-3AEA-1069-A2D8-08002B30309D} Recycle Bin. {645FF040-5081-101B-9F08-00AA002F954E} Network Neighborhood. {208D2C60-3AEA-1069-A2D7-08002B30309D} Desktop. {00021400-0000-0000-C000-000000000046} Briefcase. {85BBD920-42A0-1069-A2E4-08002B30309D} Fonts. {BD84B380-8CA2-1069-AB1D-08000948F534}You'll probably have another one in there for "My Documents".
Article ID: W13140
Filename: Delete the Briefcase Icon on Desktop.txt
File Created: 1999:04:15:16:52:02
Last Updated: 1999:04:15:16:52:02